The Butterfield Lab

A Muscle Mechanics Laboratory

Our laboratory focuses on the mechanical and physiological properties of muscle tissue during in-vivo ambulation and exercise in a number of models.  We collect direct, real time measurements of mechanical properties and performance of skeletal muscle during modified use, and measure the cellular responses thereafter.  Although it is known that muscle adapts following various modes of exercise, the mechanisms that govern these adaptive processes remain unknown at the cellular level and appear to be related to the mechanical micro-environment of individual fibers within the matrix of skeletal muscle.  The additional contributions of altered muscle function to bone and joint health is of great clinical interest, and we have devised new methodologies to further our understanding of the impact of abnormal muscle function on bone, cartilage, and ligament health during exercise

Former Lab Peeps

STATS:  Height: 5'3" Location: Calgary, AB Canada Hometown: Hermiston, OR USA Position: Postdoctoral Fellow-  Human Performance Lab University of Calgary Position in The Butterfield Lab: Doctoral Student Research Interests: Mechanical contributions of skeletal muscle adaptation to injury or imposed demands, and mechantransductive influences on the inflammatory response. Drink(s) of Choice: Delicious Oregon Microbrews (Rouge American Amber), a scrumtrulescent glass of Willamette Valley Pinot Noir, and some good Tequila…emphasis good- aged, I like my oaky-ness :-)

STATS: 

Height: 5'3"

Location: Calgary, AB Canada

Hometown: Hermiston, OR USA

Position: Postdoctoral Fellow-  Human Performance Lab University of Calgary

Position in The Butterfield Lab: Doctoral Student

Research Interests: Mechanical contributions of skeletal muscle adaptation to injury or imposed demands, and mechantransductive influences on the inflammatory response.

Drink(s) of Choice: Delicious Oregon Microbrews (Rouge American Amber), a scrumtrulescent glass of Willamette Valley Pinot Noir, and some good Tequila…emphasis good- aged, I like my oaky-ness :-)

Chris Waters-Banker PhD, ATC

Chris was born and grew up in Hermiston, Oregon, the “Watermelon Capital of the World.”  Hermiston is also home to one of the nations 6 chemical weapon stockpiles- unstable from WWII.  Oddly enough Kentucky also houses one of the other stockpiles- nerve agents don’t scare this chick.  

After playing softball for two years at a community college in Eastern Oregon, she graduated with her Associates Degree.  Chris headed off to obtain her Bachelor’s of Science degree at Oregon State University in Exercise and Sport Science, with a focus in Athletic Training.  She became a Certified Athletic Trainer in June 2008, and received a graduate assistantship position at the University of Kentucky developing a new Athletic Training program at the local middle schools in Lexington with two co-workers.  While at UK she began her basic science research under her mentor Timothy Butterfield, investigating the inflammatory response in muscle following cyclic compressive loading.  After graduating in May 2010, she decided to return to UK as a doctoral student to continue her work with Dr. Butterfield.  Chris graduated with her PhD from UK in August 2013 completing her work involving the investigation of the temporal inflammatory cell response in muscle during cyclic compression loading.  

Chris is now doing a postdoctoral fellowship at the University of Calgary with Dr. Butterfield's former advisor, Dr. Walter Herzog in Calgary, AB Canada (America's Hat).

Chris enjoys sports (playing, as well as attending, just competition in general really), competing in triathlon sprints, cooking, crocheting, making her own body butter, dancing, visiting her family, photography, and spending time with her husband and TWO English Mastiff “puppies” Achilles and Briseis who are loving the great white north.

STATS: Location: Calgary, AB Canada Position: Research Associate in the Human Performance Laboratory with Dr. Herzog Position in The Butterfield Lab: Post-Doctoral Fellow/ Honorary Lab Peep Research Interests: Muscle Mechanist with interests at the sub-cellular level investigating adaptation of skeletal muscle filaments- specifically isoform changes of Titin with exercise Drink of Choice: Gin and Tonic

STATS:

Location: Calgary, AB Canada

Position: Research Associate in the Human Performance Laboratory with Dr. Herzog

Position in The Butterfield Lab: Post-Doctoral Fellow/ Honorary Lab Peep

Research Interests: Muscle Mechanist with interests at the sub-cellular level investigating adaptation of skeletal muscle filaments- specifically isoform changes of Titin with exercise

Drink of Choice: Gin and Tonic

Tim Leonard, PhD

TIm is originally from Calgary which lies about 50 miles (or 80 km if you’re using the metric system) from the grand Canadian Rockies.  Calgary, known for its petroleum industry, was actually the first Canadian city to host the Winter Olympic games in 1988.  Inhabited by roughly 1,230,248 peeps, Calgary is also home to the Calgary Flames professional hockey team, supported fanatically by Dr. Leonard :-)  For any wrestling fans out there, Calgary also houses the Hart Family Dungeon the infamous training facility where numerous WWE and WWF have been trained.

Swept up in an oil boom in the early 70’s Calgary’s population seemed to exponentially increase to from 272,000 in 1971 to the 1,230,248 people that live there today. Boasting numerous high-rises and gorgeous natural surroundings the city of Calgary experiences cold extended winters and short summers consisting of numerous thunderstorms.  Be sure to bring your parka as you’ll want to be outside on a clear night to view the illusive northern lights- visible in the fair city of Calgary.

Tim works at the University of Calgary in the Human Performance lab with principal, and world renown investigator, Dr. Walter Herzog (if you are keeping up with the scientific family tree- Dr. Herzog is Dr. Butterfield’s mentor).  While pursuing his doctoral degree at the University of Calgary, Dr. Butterfield learned many of his instrumentation techniques from “Uncle” Leonard, who then decided to join us in Kentucky for a much too short lived, post-doc.

During his time here at Kentucky he has brought many fun and exciting techniques to our laboratory: instrumentation, titin gels, some fun coomassie blue staining, Christmas lighting, and of course lots and lots of data!  (Impressive for such a short stint, eh?!- but he is a well oiled scientific machine!!)  In the mean time he was able to sample our bourbon and even enjoy some cheesy grits :-) 

We very much appreciate his time and contributions, but most of all his company!  With quite the sense of humor he will leave us with numerous one liners, and memories of great scientific conversation.  We will miss him a great deal and of course he is always welcomed (encouraged) to visit anytime :-)

STATS: Location: Lexington, KY Hometown: Strafford, NH Position in The Butterfield Lab: Graduate Master's Student Research Interests: Effects of cyclic compressive loading on protein synthesis in hypertrophy and atrophy signaling pathways in skeletal muscle Drink of Choice: Glass of red wine or a little tequila 

STATS:

Location: Lexington, KY

Hometown: Strafford, NH

Position in The Butterfield Lab: Graduate Master's Student

Research Interests: Effects of cyclic compressive loading on protein synthesis in hypertrophy and atrophy signaling pathways in skeletal muscle

Drink of Choice: Glass of red wine or a little tequila 

Emily Brownell, BS

Emily graduated in May 2013 with her Master’s Degree in Athletic Training. Originally from a very small town in New Hampshire: Strafford (seriously small, it is comprised of 51.4 total sq miles- 2.2 of which are water).  Strafford, New Hampshire was organized in the 1700’s before the revolution as a sort of half-way point for town meetings due to the lengthy travel as the town was originally a part of Barrington.  The small town located only 595 ft above sea level is home to a mere 3,991 peeps (almost 4G’s!!) and was named in honor of Thomas Wentworth, the Earl of Strafford.  Strafford is home of the infamous Charles Simic the 15th appointed Poet Laureate Consultant in Poetry to the Library of Congress, winner of the coveted Pulitzer Prize for Poetry in 1990 (Go Charles!).

Poor Emily and her sister were outnumbered growing up by their three brothers.  During her undergraduate at Boston University she was able to use all that built up angst as motivation for her character roles performing in TWO theater groups a year.  The thespian even took on a cross-dressing role as the main character in Viola in Shakespeare’s play: The Twelve Night.

Like the rest of our lab members Emily is an animal lover.  Adopting a recovering alcoholic, depressed, pre-diabetic 20lb cat- yes you read that correctly :-)  After implementing a healthy diet and exercise program, Mitchell has lost 5 pounds and no longer diabetic.  He is currently on the “wagon” but still finds himself craving the “drink” when anyone has a glass of wine or beer is within his midst :-)  Be sure to check out our ‘photos and events’ page to see the before and after pics of this crazy cat.

Following graduation Emily accepted a position working as one of the certified Athletic Trainers at Toyota. In the future she plans to return for her PhD.

STATS:  Location: Atlanta, GA Hometown: Tecumseh, MI Position: Engineer/Entrepreneur  Research Interests: Classification of movement patterns based on joint coupling patterns. Specificity of training principles applied to injury prevention and rehabilitation. Evidence based design of diagnostic and rehabilitation tools for objectifying clinical procedures and measures. Application of electromechanical devices in diagnostic and rehabilitation tools Drink of Choice: Captain and Coke

STATS: 

Location: Atlanta, GA

Hometown: Tecumseh, MI

Position: Engineer/Entrepreneur 

Research Interests: Classification of movement patterns based on joint coupling patterns. Specificity of training principles applied to injury prevention and rehabilitation. Evidence based design of diagnostic and rehabilitation tools for objectifying clinical procedures and measures. Application of electromechanical devices in diagnostic and rehabilitation tools

Drink of Choice: Captain and Coke

Tommy Cunningham, PhD

Tommy, our former resident engineer, grew up in Tecumseh, Michigan, a modest town of about 8,500 people.  Interesting fact about Tecumseh (named after Chief Tecumseh), it is the final resting place of Don Juan, General George Armstrong Custer’s horse who was sent to a friend of his living in Tecumseh after his death.  Tecumseh was also voted #93 out of 100 best small towns to live in by CNNmoney in 2009.

Tommy has been a faithful UK student through and through.  As an Undergrad he received his bachelor of science in Mechanical Engineering, his master’s in Biomechanics, and is currently a doctoral candidate, expected to graduate this Spring (2011) with his doctorate in Biomechanics.

Tommy is currently “living the dream” in Atlanta, and enjoys playing seasonal competitive sporting activities- main sports: golf, soccer, and softball.  While in our lab he also enjoyed misplacing tools, and running around town finding random items to complete our sweet inventions.

STATS: Location: Cambridge. MA Hometown: Oxford, MA Position in The Butterfield Lab: Post-Doctoral Fellow Research Interests: Mechanistic contributors to early-onset osteoarthritis, rehabilitation for joint injuries, hip mechanisms  

STATS:

Location: Cambridge. MA

Hometown: Oxford, MA

Position in The Butterfield Lab: Post-Doctoral Fellow

Research Interests: Mechanistic contributors to early-onset osteoarthritis, rehabilitation for joint injuries, hip mechanisms

 

Maureen worked in The Butterfield Lab from Fall 2009 to Spring 2011. She is currently working at Harvard University.